Susceptibility genesindicate that the environment plays no role in developing obesitymay predispose…

➤ How do susceptibility genes interact with the environment?
Genes and environment interact through gene–environment interplay. Genetic predisposition shapes responses to food cues, stress, and physical activity. Environmental factors like high-calorie diets, sedentary lifestyle, sleep loss, and food access can trigger or amplify genetic risk. Epigenetic changes and developmental timing also alter gene expression across life stages.