Which is the primary purpose that preoperative antibiotics are prescribed for a client who is…

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➤ How soon before incision should prophylactic antibiotics be administered, and why does timing matter?
Give prophylactic intravenous antibiotics within 60 minutes before the skin incision to ensure bactericidal tissue levels at the time of contamination. For agents requiring longer infusion, start within 120 minutes. Redose during prolonged operations or with excessive blood loss based on the drug’s half-life to maintain effective concentrations throughout the procedure.

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