➤ Is there a safer alternative to esomeprazole for stress ulcer prophylaxis in ventilated patients?
H2 receptor antagonists and sucralfate are alternatives. H2 blockers reduce acid less predictably but may lower pneumonia risk in some studies. Sucralfate protects mucosa without raising pH, so it may reduce infection risk but is less effective against clinically significant bleeding. Choose based on individual bleeding versus infection risk and institutional protocols.
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