Question 13Which of the following adverse effects is specific to the biguanide diabetic drug…

➤ How can gastrointestinal side effects from metformin be minimized?
Start with a low dose and titrate slowly. Take metformin with meals, split doses, or switch to an extended‑release formulation to reduce nausea, diarrhea, and abdominal pain. Reinforce hydration and consider dose reduction if symptoms persist. Most GI effects improve within weeks with gradual adjustment.