2. Why is gabapentin used as an adjunct during alcohol withdrawal?
Gabapentin modulates GABAergic tone and voltage‑gated calcium channels to reduce neuronal hyperexcitability that drives withdrawal symptoms. It may lower seizure risk, ease autonomic symptoms, and improve sleep and craving. Clinical trials support its benzodiazepine‑sparing role in mild to moderate withdrawal, with attention to sedation and renal function.
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