➤ Why do antipsychotic medications cause akathisia and which drugs carry higher risk?
Antipsychotics cause akathisia mainly through dopamine D2 receptor blockade in the nigrostriatal pathway. High-potency typical antipsychotics, rapid dose escalation, and long-acting injections raise risk. Some atypical agents such as aripiprazole can also trigger symptoms. Patient factors like younger age, female sex, and prior movement disorders increase susceptibility.
Leave a Reply