a patient with a heart valve replacement currently on warfarin is being treated for an ischemic…

➤ How should INR values affect eligibility for intravenous alteplase?
An INR of 1.7 or lower is generally required to proceed with intravenous alteplase. Values above 1.7 indicate increased bleeding risk and are considered a contraindication to standard fibrinolysis. Always confirm INR immediately, repeat if needed, and consult neurology and hematology before making a treatment decision.