Mr. Green is a 63 -year-old man with heartburn (gastroesophageal reflux disease [GERD]). When it…

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➤ How do clinicians confirm esophagodynia or diagnose GERD flares?
Clinicians use a targeted history and exam, then trial acid suppression to assess response. Upper endoscopy checks for erosive esophagitis or complications. Ambulatory 24‑hour pH/impedance testing and esophageal manometry help when symptoms persist or before surgery. Biopsy can exclude eosinophilic or infectious esophagitis.

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