➤ Why is flumazenil used cautiously in neonates and infants?
Flumazenil can trigger acute benzodiazepine withdrawal and seizures, particularly with prior exposure or co-ingested proconvulsants. Neonates also have immature metabolic pathways and variable sensitivity. Clinicians give small incremental doses and maintain continuous monitoring of airway, breathing, circulation, and neurologic status after administration.
Leave a Reply