Question 33Microorganisms using theroute of entry invades tissues via injections, bites, cuts,…

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➤ Why does parenteral exposure increase the chance of systemic spread?
Parenteral exposure bypasses first-line defenses and can introduce pathogens directly into circulation or deep tissues. The immune filtering present at skin and mucosa is avoided, and the delivered inoculum can be larger. These factors raise the likelihood of bacteremia, sepsis, or deep-seated infections without timely intervention.

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