➤ How does dose and monotherapy versus polytherapy affect fetal risk?
Risk of congenital malformations increases with higher doses and polytherapy. Monotherapy at the lowest effective dose carries lower risk. Avoiding valproate, minimizing number of drugs, and tailoring treatment can reduce fetal harm. Consult your neurologist to weigh seizure control against teratogenic risk and consider preconception planning.
Leave a Reply