Which assessment will differentiate muscarinic and nicotinic stimulation from cholinergic…

3.
➤ Can blood pressure changes reliably differentiate muscarinic and nicotinic effects?
Blood pressure alone is unreliable. Muscarinic stimulation usually causes vasodilation and hypotension through endothelial M3-mediated nitric oxide. Nicotinic activation at ganglia or the adrenal medulla can produce mixed sympathetic responses and hypertension. Always assess heart rate, secretions, and muscle signs alongside blood pressure.